Endocrine Abstracts

Adrenal insufficiency is not commonly associated with a finding of bilateral enlarged adrenal gland when diagnosed in late adulthood. Various cases in the literature to date seem to indicate that the combination of these two findings may be suggestive of adrenal lymphoma. Our patient was initially referred to Gastroenterology with weight loss, nausea and early satiety from where he was referred for a whole body computed-tomography (CT) scan as part of a screen for malignancy. ...

Objectives: Pituitary Apoplexy, either as a result of haemorrhage or infarction, remains a rare but serious Endocrine Disorder, requiring urgent clinical assessment and management. The British Endocrine Society (BES) has set out recommendations regarding the diagnosis and management of pituitary apoplexy, but there remains little published literature depicting this. The aim of this study was to compare our current Management practise of Pituitary Apoplexy with the recommendati...

Introduction: In 2003, the UK National Institute for Clinical Excellence (NICE) established guidelines on the use of GH in adults. These guidelines state that recombinant GH should be used only for adults with a severe GH deficiency that severely affects their quality of life. To assess current practice in relation to these guidelines, a review of patients receiving GH treatment was performed. The aims were to assess if adults with GH deficiency met NICE criteria for GH therap...

We report an interesting case of a rare presentation of hypercalcemia in a 27-year-old pregnant woman with history of Uterine fibroids. The patient arrived at the emergency department with two weeks history of worsening lower abdominal pain. She had resorted to sleeping in a sitting position due to the intensity of pain. There was no vaginal bleeding and bowels were not opened for four days. Physical examination revealed dehydration, tenderness in the lower abdomen with an abd...

Introduction: Hypophysitis is the inflammation of the pituitary gland, characterised by hypopituitarism and pituitary enlargement. It can occur as primary (commonly lymphocytic, granulomatous or xanthomatous) or secondary to systemic disease, immunotherapy or sella-based pathologies.Case Presentation: A 30-year-old female was admitted to hospital with headache, fatigue, low mood and blurred vision, 3 months after having ...

Background: Parathyroid Carcinoma (PC) is a very rare endocrine malignancy. Unlike Parathyroid Adenoma (PA) and Parathyroid Hyperplasia which represents 80% and 15-20% cases of primary hyperparathyroidism (PHPT) respectively, PC only constitutes 1-2% of cases. Herein we present a clinical case of PC following a low-impact trauma.Clinical case: A 50-year-old Bulgarian female presented with a pathological mid-shaft fracture of her right femur following a t...

A 66 year old lady with a previous diagnosis of Retinitis Pigmentosa (RP) was referred to our endocrine clinic with excessive sweating and was also noted to have hypertension, thin skin, extensive bruising and central obesity. Her past medical history included a benign thyroid nodule, gastric erosions, osteoporosis, hyperlipidaemia and depression. On examination, blood pressure was 164/86 mmHg and BMI was 30.7 kg/m2 with central obesity. Biochemical testing revealed...

A 41 year old man was initially referred to lymphoedema clinic. He had leg swelling of 10 years duration but was otherwise fit and well. Examination revealed marked lipohypertrophy affecting his thighs bilaterally. There was no oedema and his distal lower limbs were normal. MRI investigation confirmed focal lipohypertrophy. Biochemical investigation revealed a very low albumin of <10 g/l, a low calcium of 1.96 mmol/l and hyperlipidaemia (cholesterol 9.3 mmol/l, LDL 6.4 mmo...